Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

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Contributors

This material was contributed to by:

orcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoMartin Čech avatar Martin ČechMehmet Tekman avatar Mehmet Tekmanorcid logoKrzysztof Poterlowicz avatar Krzysztof Poterlowiczorcid logoHelena Rasche avatar Helena Rascheorcid logoMaria Doyle avatar Maria DoyleTorsten Houwaart avatar Torsten Houwaartorcid logoArmin Dadras avatar Armin DadrasDevon Ryan avatar Devon RyanFidel Ramirez avatar Fidel Ramirezorcid logoBjörn Grüning avatar Björn Grüningorcid logoKhaled Jum'ah avatar Khaled Jum'ahorcid logoFlorian Heyl avatar Florian Heylorcid logoMallory Freeberg avatar Mallory FreebergNiall Beard avatar Niall Beardorcid logoWolfgang Maier avatar Wolfgang MaierJoachim Wolff avatar Joachim WolffVerena Moosmann avatar Verena MoosmannWilliam Durand avatar William Durandorcid logoYvan Le Bras avatar Yvan Le Brasorcid logoAnika Erxleben avatar Anika ErxlebenEkaterina Polkh avatar Ekaterina PolkhGildas Le Corguillé avatar Gildas Le CorguilléVivek Bhardwaj avatar Vivek BhardwajLeily Rabbani avatar Leily Rabbaniorcid logoPavankumar Videm avatar Pavankumar Videmorcid logoNicola Soranzo avatar Nicola SoranzoMélanie Petera avatar Mélanie PeteraAnup Kumar avatar Anup Kumarorcid logoLucille Delisle avatar Lucille Delisleorcid logoKatarzyna Kamieniecka avatar Katarzyna Kamienieckaorcid logoBérénice Batut avatar Bérénice Batutorcid logoMo Heydarian avatar Mo HeydarianFriederike Dündar avatar Friederike Dündar

Funding

These individuals or organisations provided funding support for the development of this resource

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de.NBI
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CRC992
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UFR
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ELIXIR Europe